The C-NORA project

Although ”transport” may imply different notions for different scientific fields, the feature of incorporation of interacting system components through which ”information” is propagated remains invariant. Biological transport systems is an example whose significance has become evident with the recent outbreak of COVID-19 spreading. Blood transport in cardiovascular systems falls also under this category. The urgent need of design of efficient/safe, epidemics spreading suppression and congested blood transport monitoring, strategies is apparent, considering the potential, significant socioeconomic impact. However, the continuum, spatiotemporally-varying nature of such interconnected systems, in addition to dynamic complexity and limited available control authority, hamper development of systematic feedback control design and analysis methodologies. C-NORA aims at introduction of a pioneering holistic framework for systematic, computationally tractable control design and analysis of large-scale, interacting, distributed parameter transport systems, which i) harmonizes control at micro-macro levels, ii) accounts in design for all essential dynamic phenomena, iii) compensates adverse effects of limited control authority in design, and iv) develops ad hoc tools for system-specific analysis. C-NORA new control design and analysis tools will be demonstrated in distributed parameter, epidemiological/ cardiovascular transport systems and will be validated in numerical simulation.

C-NORA’s main objectives are the following:

OBJ 1: Delay compensation for switched nonlinear systems with robust-by-design implementation.

The aim of the first objective is to introduce new control design and analysis methodologies for simultaneous compensation of input delay, switching, quantization, and sampling effects for general nonlinear systems, guaranteeing-by design-robustness to implementation errors.

OBJ 2: Control and estimation of hyperbolic switched systems with robust-by-design implementation.

The aim of the second objective is to introduce a new control design and analysis framework for more complex infinite-dimensional systems, which could be described by switched hyperbolic PDE systems, under adverse implementation effects.

OBJ 3: Micro-macro control of continua of interacting distributed parameter transport systems.

The aim of the third objective is to introduce systematic and constructive, micro-macro control and analysis approaches for interconnected, and, eventually, continua-of-interacting distributed parameter transport systems.

OBJ 4: Control and analysis of infinite-dimensional epidemiological and cardiovascular transport systems.
  • OBJ 4a. Epidemiological distributed parameter transport system. C-NORA will address systematic design and analysis of control strategies for epidemiological systems, accounting, simultaneously, for the essential dynamic phenomena featured, delivering novel spreading suppression and estimation solutions with certified efficiency and robustness guarantees, also validated in realistic scenarios through extensive, numerical simulation.
  • OBJ 4b. Cardiovascular distributed parameter transport systems. C-NORA will address development of advanced, real-time feedback monitoring and control strategies for cardiovascular transport systems, enabling timely and accurate automated detection and action implementation, via development of systematic control, estimation, and analysis methodologies for blood transport and their simulation validation.
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